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Welcome to eFlash, the monthly Accelrys newsletter that provides the latest news on product releases, events, resources, and more. In this month's issue:
- April Feature: Symyx Notebook by Accelrys Advances Drug Development
Product News:- Resources:
- Events:
- On the Web:
- Featured Videos:
Symyx Notebook by Accelrys efficiently connects scientists, instruments and software within the analytical, process and formulation areas of drug development.
With the average revenue for a top-20 blockbuster drug hovering around $16.6M/day/drug, every day saved in drug development offers significant ROI opportunities for Pharma Dev organizations.
Last month’s release of Symyx Notebook by Accelrys v. 6.6—adding formulations capabilities to the notebook’s existing support for analytical and process scientists—spotlights drug development and the many ways an ELN helps accelerate therapeutic substances from research through development to early manufacturing.
Symyx Notebook by Accelrys is a multidisciplinary electronic lab notebook (ELN) supporting analytical, process and formulation scientists working in chemistry, manufacturing and controls (CMC). This is the area concerned with the nature of drug substances and drug products and how to select, optimize, validate and scale-up drug development procedures using efficient, validated and compliant processes.
The ELN offers out-of-the-box configurations and productivity-enhancing capabilities that accelerate drug development by providing consistent, end-to-end documentation of the design, execution, analysis, and reporting of results, as well as tight integration with software and instrumentation (CDS, LIMS, balances, etc.). The ELN reduces re-invention as scientists can quickly learn from what others have documented. It also reduces experiment repetition as scientists can easily see what has been done before. Faster information transfer moves recipes and SOPs quickly to the next step of the workflow. Improved coordination and tracking means scientists can assign tasks, link experiments and rapidly import results and analyses generated by colleagues.
Sitting within the Enterprise Lab Management pillar of the Accelrys Enterprise R&D Architecture, Symyx Notebook by Accelrys meets drug development’s need for an upgraded informatics environment that drives improved efficiency and compliance through tighter integration of scientists, instruments and software.
For more information, attend the on-demand webinar, “Five Ways to Accelerate Drug Development with an ELN.”
Accelrys QSAR Workbench cuts model development time from days to hours, accelerating the identification of successful hits earlier in the research process and potentially reducing the number of costly lab experiments.
Accelrys Modeling & Simulation: Improving Outcomes
with Predictive Science and the QSAR Workbench
As a key pillar of the new Accelrys Enterprise R&D Architecture, the Accelrys Modeling & Simulation Suite offers a unified platform for the automation and expert use of predictive science, improving outcomes, quality and sustainability in R&D. The suite, which includes the recently released Accelrys QSAR Workbench, gives R&D organizations access to the broadest, deepest predictive science capabilities ranging across small molecules, biomolecules, chemicals and materials.
The Accelrys Modeling and Simulation Suite includes Discovery Studio® software for life sciences R&D, Materials Studio software for scientists working in chemicals and materials R&D, the Pipeline Pilot™ Life Science and Materials Modeling and Simulation Collections, and the new QSAR Workbench. Developed in collaboration with pharmaceutical company GlaxoSmithKline and available as a packaged service offering from Accelrys Professional Services, the Accelrys QSAR Workbench automates and accelerates the development, validation and deployment of predictive Quantitative Structure-Activity Relationship (QSAR) models, improving decision making in R&D organizations. The unified Pipeline Pilot platform underlying QSAR Workbench extends the productivity and reach of expert statisticians within an R&D organization, capturing best practices of QSAR design, streamlining model development, reducing errors and automating manual, tedious and error-prone processes so that every project benefits from a model. Optimal models can then be saved and deployed more widely for immediate use by others.
Read the Modeling & Simulation Press Release Read the QSAR Workbench Press Release
For hands-on experience with Accelrys QSAR Workbench, register for a free 30-day online trial.
Case Study: “Building Novel Applications with Pipeline Pilot to drive Next Generation Sequencing”
Learn how the release of the Next Generation Sequencing (NGS) Collection for Pipeline Pilot is enabling scientists and informaticians to build and perform complex analyses of DNA sequence information in dramatically streamlined fashion. In this case study, Richard Carter of Oxford Nanopore Technologies Ltd. highlights some key benefits of the NGS Collection including simpler DNA sequencing workflows such as quality assessment and filtering, visualizing gene content or density, identifying and comparing SNPs and other variants and comparing RNA expression across experiments or individuals.
Case Study: “Elan Fosters Collaboration with Integrated Electronic Lab”
Find out how Elan Pharmaceuticals accelerated the research cycle by integrating Isentris, Pipeline Pilot, Symyx Notebook by Accelrys and the Direct data cartridge to provide a single view of chemical and biological data. Scientists at a partner site were also enabled to securely deposit research results in the ELN—making legacy knowledge and critical intellectual property readily accessible to scientists.
2011 North American User Group Meeting
Join us on the east coast, May 17-19, for the 2011 Accelrys North American User Group Meeting (UGM). The 2011 UGM will be held at the beautiful Hyatt Regency Jersey City located across the Hudson from Lower Manhattan.
Preliminary Agenda Now Available
Take a look at the great lineup of customer presentations, breakout sessions, workshops and round table discussion sessions scheduled for the UGM.
Call for Posters – New for 2011
The 2011 UGM will feature a poster session where conference attendees can showcase their research. If you are interested in being considered for a poster presentation, please submit a title and brief abstract describing the research content of the poster to abstracts@accelrys.com. Deadline is Friday, April 22.
Hotel Discount Deadline
Remember to book your hotel room by April 27th to secure the UGM discount rate of $229.
Group discounts are still available!
LEARN MORE REGISTER NOW AND SAVE
Upcoming Webinars
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Integration of Molecular Discovery's GRID within Discovery Studio 3.0 |
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Integration of Cresset's FieldStere within Discovery Studio 3.0 |
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Accelerate your Process Chemistry with an ELN |
Upcoming Conferences
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BioIT World 2011 Experience Pipeline Pilot and Discovery Studio as never before on one of the world’s most advanced multi-touch displays, the Perceptive Pixel 55” HD LDC. While at the booth, you can also demo the latest version of Symyx Notebook by Accelrys, the new NGS Collection for Pipeline Pilot and our Cheminformatics suite. Don’t Miss These Accelrys Presentations: The Pipeline Pilot NGS Collection: A New Approach to the Challenges of NGS Data Analysis |
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Materials Research Society (MRS) At MRS this spring our materials modeling and simulation experts will showcase the Pipeline Pilot™ enterprise R&D platform and Materials Studio™ modeling and simulation application for chemicals and materials R&D and drug development. We’ll also present our new QSAR Workbench solution that automates and speeds the development, validation and deployment of predictive QSAR models. Stop by the booth for a chance to win an iPod Touch! |
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Drug Delivery & Formulation America 2011 Join us in La Jolla where our Electronic Lab Notebook (ELN) and modeling services experts will be on hand to answer questions around the use of ELNs and in silico approaches to accelerating products from lab to patient. We will also host a workshop on Informatics in formulation development. |
Recent Blog Posts
- Synthesis Planning and Route Design with an ELN — Integrating an ELN with a powerful chemistry search and decision support application can cut the searching of commercial literature and paper notebooks from days to minutes, significantly speeding synthesis planning.
- Supporting QbD with Enterprise Lab Management and Standards — A multidisciplinary ELN in conjunction with common “method execution” industry standards, which are being developed today, are essential for efficient, compliant drug development programs.
In the News
- “Accelrys Announces the Accelrys Modeling and Simulation Suite, Providing a Unified Platform for Predictive Science” (Press Release, March 29, 2011)
- “Accelrys Extends Impact of Modeling and Simulation with New QSAR Workbench” (Press Release, March 29, 2011)
- “Accelrys Announces Multidisciplinary ELN Supporting Analytical, Process and Formulation Scientists in Drug Development” (Press Release, March 24, 2011)
- “UCD College of Engineering, Mathematical and Physical Sciences Agrees to License Accelrys Software for Academic Collaboration” (Science Foundation Ireland, March 21, 2011)
- “Accelrys and Oxford Nanopore Enter Software Partnership for DNA Sequencing Data Analysis” (Press Release, March 16, 2011)
