About Us

Committed to speeding innovation for science-driven organizations, from product ideation through commercialization.

Events

Visit us at PEGS in Boston

Conference Website

Event Date

25 — 29 April, 2016

Event Location

The Seaport World Trade Center
Boston, USA
Booth #121

Join us at the 12th Annual PEGS Boston Conference, April 25- 29th. Stop by booth 121 where our experts will be showcasing BIOVIA Biologics - A comprehensive software solution designed to help with the discovery and development of biotherapeutic candidates.

Hear from Dassault Systemes Ralph Eckenberg, Integrative Therapeutics on Monday, April 25th at 12:50pm in the Luncheon Presentations.

In silico Approaches for Early Assessment of Immunogenicity

Abstract

Unexpected adverse events are reasons of drug development failures that contribute to the attrition rate in pharmaceutical industry. A possible cause specifically associated to Biotherapeutics (peptides/proteins) is immunogenicity: the ability of some biotherapeutics to trigger immune responses that conduct to the generation of antibodies specifically directed against the drug. This immune response can possibly reduce the treatment efficacy and provoke adverse effects. Predicting immunogenicity is proving difficult because of the complexity of the underlying biological processes. We present here an informatics application based on modeling and simulation approaches that can help the pharmaceutical R&D to prioritize promising drugs with respect to the immunogenicity risk.

We look forward to seeing you in Boston!

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