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Webinar Series: Accelrys Biological Registration

Learn how Accelrys is setting the bar in biological registration. We will demonstrate how Accelrys Biological Registration can significantly reduces the risk inherent in failing to register intellectual property while enabling knowledge sharing among biology and other research scientists; all while providing the flexibility to meet your organizations needs.

More webinars will be added to the series, so please check back often.

Archived Webinars

Date Title and Speaker
May 26

Intro to Accelrys Biological Registration
Speaker: Mark Hughes,PhD, Senior Product Manager, Accelrys

The inherently complex nature of cell lines, plasmids, proteins, antibodies and vaccines makes a biological registration system challenging. Yet such systems are needed so that researchers and companies can track these entities and their relationships, creating critical intellectual property positions as well as connections to past research and manufacturing processes.

Patterned on the services of registration systems for chemical entities, which are well-known and entrenched in the drug discovery process, the Accelrys Biological Registration system is an "intelligent" solution for registering, associating, searching and retrieving data for entities such as siRNA, plasmids, cell lines, proteins, antibodies, vaccines and future biological entities.

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June 9

The Biology of Registration: Science vs. Process
Speaker: Todd Pihl, PhD, CTO, Vice President, R&D,HumanWorkflows, LLC

Registration revolves around a seemingly simple question, namely, "What is this thing, and is this thing unique?" In registration of small molecules, this is a fairly simple question because there are generally accepted and well developed standards describing the exact structure of chemical entities and therefore their identity. However, when moving into the biological realm, there is a distinct lack of agreement on what makes two biological entities the same or different. For example, if a protein is expressed in two different cell lines, one scientist may consider them to be the same thing because they share the same amino acid sequence while another scientist may consider them to be different because of different glycosylation patterns. Similarly, in working with cell lines, it is generally accepted that any time a cell line is passaged, it is somewhat different from its parent. However, for practical reasons, many scientists will consider the new batch of cells to be the same as the batch from which they were derived. Of course there are other situations, such as putting a cell line through a limiting dilution, where the individual clonal populations are all considered to be unique.

What these realities of biological entities demonstrate is that, unlike the world of small molecules, rules for identity can be more fluid, and dependent on the needs of specific end-users. As such, a biological registration system must be flexible enough to accommodate different business rules for different needs, yet maintain a reliable backend infrastructure that allows the system to be maintained, supported, and updated. In this talk we will explore this intersection between biological fact and laboratory practice and its influence on how the Accelrys Biological Registration system works, as well as look forward and outline a way to incorporate these hard-learned lessons into future entities or customization of existing entities.

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