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New Tools for Identification and Analysis of Protein Aggregation Using Discovery Studio

In the growing area of biologics discovery and development, protein aggregation has become a key area of focus for the successful transition of a therapeutic candidate from the lab into the clinic. Unfortunately, aggregation and protein instability are not unexpected events when molecules are subjected to high stress environments such as room temperature long term storage at high concentration levels, which are requirements for biological drug formulation. So to create molecules that can withstand such stressful environments while retaining their therapeutic properties, scientists need access to tools that can fully characterize and provide molecular functional insights for their molecules of interest.

In this webinar, we will showcase  a new module in Discovery Studio dedicated to the identification of sites of aggregation using the experimentally validated Spatial Aggregation Propensity algorithm developed by Prof. Trout at MIT. In the webinar we will provide some examples of the type of analysis that we can now do with a long term goal of helping design better biological molecules.

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