Increase your research efficiency
& make better decisions, faster
Increase your research productivity by collecting, analyzing, reporting and sharing information across the R&D organization to make better decisions, faster.
- Scientific Business Intelligence White Paper: Get access to the leadingScientific Business Intelligence White Paper
Toxicology
Recent chemical and cosmetics regulations have left toxicologists struggling to meet regulatory compliance requirements. In addition to REACH, significant amendments to the EU Cosmetics Directive have come into force. For example, the seventh amendment to the Cosmetics Directive has led to a ban on animal testing for certain types of reactions. As a result, scientists are being asked to make maximum use of existing data as well making maximum use of silico methods.
Accelrys offers a range of capabilities for both the modeler and the experimentalist to maximize their use of existing data as well as making it easier to apply in silico methods.
Scientific data management capabilities:
- Easily access and manage scientific data scattered across the R&D organization, including data from disparate sources and multiple applications such as data from in silico methods, images from in-vitro tests, and analytical characterization.
- See different views of your data, including side-by-side comparisons of information from different data sources and data that was processed in alternate ways.
- Incorporate your results into easily customizable, interactive reports with drill-down capabilities to easily generate reports for the different levels of end users and management.
In-silico capabilities:
- Conduct QSAR analysis, chemical similarity searching and other read-across techniques to maximize the value of all data.
- Automatically predict biodegradation products and a range of physical properties to ensure regulatory compliance by thoroughly and systematically identifying breakdown products.
- Perform toxicity assessments using in-silico tools including the widely used TopKat product, new extensible models, and state-of-the-art model building tools.
Accelrys’ in-silico and scientific data management capabilities allow toxicologists to streamline monitoring, analysis, and reporting of chemical by-products to help ensure compliance with regulations.
Formulations
Many scientists are frustrated with how difficult, time consuming and expensive it is to create a new, optimal or improved formulation. As they gain this knowledge, they must determine how best to share their new expertise with others in the organization in a coherent and reproducible form. Some of the specific problems scientists face include:
- Tracking data generated by thousands of formulations spread across different databases and stored in different formats
- No clear insight into what experiments to run next
- Wasting time repeating experiments because previous information hasn’t been retained
Acclerys provides the software tools that allows scientists to:
- Easily access and manage scientific data scattered across the R&D organization, including data from disparate sources and multiple applications
- Gain reliable access to data from past experiments resulting in reducing unnecessary re-testing
- Reduce the number of experiments needed to achive optimal formations by employing superior analytics and decision support capabilities that establish a rational basis for performing a series of experiments
- Leverage the experience of your lead formulators by sharing their best practices across the organization
Increase efficiency in the formulation or re-formulation process by the collection, mining and analysis of data with intelligent decision support capabilities and share information across the organization to make better R&D decisions, faster.
Skin Care and Dermatological Applications
Understanding and affecting the interaction of formulations with skin is one of the most crucial areas for research and product development in Personal Care and Dermatological products. Factors that need to be considered include appearance and feel, permeation and delivery of any active ingredients, chemical stability and product safety.
Accelrys software tools support the scientist developing skin care applications in a number of ways, including:
- Image analysis tools to enable you to seamlessly process, standardize and integrate all of your images and associated data when conducting skin care test series.
- Superior analytics and decision support capabilities to help uncover unexpected ingredient interactions, and enable you make rational choices on what to test next when creating new or improved formulations.
- With limitations on in-vivo tests, in-silico skin models complement in-vitro models. For example, it is easy in an in silico model to test the behavior of different types of skin or to study the likely effect of alterations resulting from disease.
- Build customized models of permeation and extend publicly available QSPR models for screening of compounds regarding skin penetration.
- Aid the development of dermatological controlled release products by simulating how active ingredients are released into the skin from delivery vectors such as micelles. See how Galderma did this.
- Screen compounds and make a quick assessment of potential skin irritation, thereby reducing experimental testing.
Image Analysis
Seamlessly process, standardize and integrate all of your images and associated data. Pipeline Pilot’s user-friendly visual programming can be used for a myriad of image related workflows, from building custom image processing algorithms to improving Quality Control and reporting. No computer programming skills needed!
Our processing and analysis capabilities rival even the most sophisticated image processing packages available for building and modifying image algorithms. Use Pipeline Pilot to:
- Extract and manipulate regions and sub-regions in color and grayscale images
- Calculate advanced intensity, shape and morphology statistics within regions
- Apply learning and modeling techniques to image regions
Integrate images and associated data with other data types to easily implement business rules for improved QC. Use interactive reports with image to data links, giving a visual verification for error and accuracy between data and image. Then, apply Pipeline Pilot’s easy to use web interface to deploy image data workflows throughout your organization.
Image Analysis Demo (2:04)
Image Processing Methods (PDF)
Acclerys provides the software tools that allow scientists to:
- Easily access and manage scientific data scattered across the R&D organization, including data from disparate sources and multiple applications.
- Automate and streamline tedious development processes, allowing you to spend more time on the science and less time on the mundane administrative tasks.
- Reduce the number of experiments you need to run with superior analytics and decision support capabilities that use rigorous statistical analysis to enable rational experimental design.
- Avoid wasting time repeating experiments because you can’t find the information.
- See different views of your data, including side-by-side comparisons of information from different data sources and data that was processed in alternate ways.
- Incorporate your results into easily customizable, interactive reports with drill-down capabilities to generate reports for the different levels of end users and management.
- Share results throughout your organization via web-based portal, dashboards or industry standard tools like Microsoft Sharepoint.
About Pipeline Pilot
- 3-Minute Introduction to Pipeline Pilot
- Scientific Business Intelligence White Paper
- CPG Industry White Paper
“With its Pipeline Pilot platform, Accelrys has brought about a paradigm shift in the handling and management of critical scientific information and its application in business analytics...Accelrys has synergized its excellence in both focus areas and has ensured its rapid growth in the Scientific Business Intelligence (Sci-Bi) market. With leading Fortune 500 companies as its clients, Accelrys is far ahead of its competition.”