BIOSTER

Database of bioanalogous molecules for use in analogue design

The BIOSTER database is a critical compilation of thousands of bio-analogous molecule pairs (including drugs, agrochemicals and enzyme inhibitors) that have been selected from primary literature references by academic expert Dr. István Ujváry (The Hungarian Academy of Sciences).

The BIOSTER database features:

• over 14,300 active molecules (drugs, agrochemicals and enzyme inhibitors, pro-drugs, etc.)
• keywords indicating the mode of action
• cross-referenced information to the papers that report each active compound
• search capabilities by substructure or keyword for finding compounds or fragments
• navigation tools for exploring the database to uncover previously untested isosteres
• storage and display of molecule pairs as 'transformations' with the possibility to search individual molecules or replaceable fragments using a single substructure query