Collaborative Science

Accelerating time to market and driving innovation with collaboration, knowledge based under-standing and prediction.


BIOVIA Discovery Studio

Built on the BIOVIA Foundation, Discovery Studio is BIOVIA’s comprehensive predictive science application for the Life Sciences

Announcing BIOVIA Discovery Studio 4.5

  • Compatible with the latest release of BIOVIA Foundation 9.5
  • New! Antibody Modeling Cascade
    • Automatically generate accurate and robust 3D model structures for one or more antibody Fab or Fv regions, starting from a set of light and heavy antibody chain sequences
  • New! Protein property predictions f(pH)
    • Includes new features to calculate mean atomic charges, average dipole moment, net charge, electrostatic contribution to the solvation energy as a function of pH
    • Together, these properties are useful in studying protein solubility and viscosity, protein-protein docking and enzyme activity
  • New! CHARMM Substructure typing engine
    • Uses sub-structure pattern matching to assign atom types for charmm36, charmm27, and charmm22 forcefields
    • This provides improved typing for many chemical functional groups, including carbohydrates, lipids, and ligands, etc.(e.g., retinol.)
    • Handles modified amino acid residues such as glycosylated Asn
    • Includes the ability to import and assign custom atom types and parameters
  • New! WebGL 3D visualizer
    • This release includes the first prototype version of our next generation Web Viewer
    • Based on WebGL technology that is now widely available in modern web browsers, it delivers 3D rendering performance comparable to the Discovery Studio client
  • Updated 2D Ligand Interaction Diagram
    • Includes support for the extended library of favourable, unfavourable and unsatisfied non-bond interaction types
    • Available via scripting and as a Pipeline Pilot component

System Requirements for Discovery Studio 4.5

What's New in Discovery Studio 4.5

With Discovery Studio you can:

  • Investigate and test hypotheses in silico prior to costly experimental implementation, thus reducing the time and expense involved in bringing products to market
  • Drive scientific exploration from target identification to lead optimization with a wealth of trusted life science modeling and simulation tools
  • Leverage an open and scalable platform to automate processes, create and deploy custom workflows, and integrate data types, databases, and third-party or in-house tools
  • Enhance personal productivity and boost team collaboration by enabling researchers to share data and make better informed decisions

Citations and Acknowledgements

We love to hear about Discovery Studio being used in new and interesting ways. If you want to cite the use of a BIOVIA Software product in a publication, we recommend the following format:

Ref. Dassault Systèmes BIOVIA, Discovery Studio Modeling Environment, Release 4.5, San Diego: Dassault Systèmes, 2015.

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