The structure-searchable bioactivity database of toxic chemical substances contains data from in vivo and in vitro studies of:
Tumorigenicity and carcinogenicity
Skin and eye irritation
Multiple dose effects
Scientists from a variety of disciplines use the database:
Toxicologists at pharmaceutical and chemical companies
Drug Safety scientists, both discovery and preclinical development
Drug metabolism and pharmacokinetics (DMPK) scientists
Safety officers in pharmaceutical companies – especially in synthesis scale up and production facilities
Toxicity Database can be used in conjunction with Accelrys Metabolite Database. A single click enables structure browsing in either database to transfer and view relevant toxicity and biotransformation data.
EnlargeUse the Accelrys Toxicity Database to view toxicity information in new patent applications for drugs.