AREA OF SCIENCE: BIOSCIENCES
Answer scientific questions across a broad range of bioscience areas from biotherapeutics to translational research.
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Biomarkers
In biomedicine, biomarkers play a key role in diagnosing diseases, identifying the best therapies for specific patient subpopulations, and monitoring treatment response. However, the enormous volume of disparate data that must be analyzed, along with the frequent availability of new analysis techniques, presents a data management and analysis challenge that can threaten project success.
Accelrys' scientific informatics platform, Pipeline Pilot, helps you overcome this challenge, freeing you to focus your effort where it matters most — identifying disease and treatment markers. You can manage, integrate, and analyze enormous amounts of disparate data, including ‘omics and imaging data, patient phenotypes, and data from scientific literature. And, as each new biomarker program is initiated, you can easily create project-specific protocols, quickly integrating new third-party applications and algorithms without destroying existing workflows.
When it comes time for in vivo and in vitro experimentation, Symyx Notebook by Accelrys for Biology improves operational efficiencies and lowers costs by enabling you to plan, execute, and record experiments using a single notebook enterprise-wide.
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Pipeline Pilot Create and automate workflows by graphically combining components for data retrieval, filtering, analysis, and reporting.
Pipeline Pilot Component Collections:
NGS Collection: Providing unmatched power and flexibility, the NGS Collection lets you perform genome assembly, mapping, variant detection, RNA-Seq, and ChIP-Seq experiments on data from all major NGS instrumentation platforms.
Additional Biology Collections: Perform advanced analyses on your ‘omics data using the robust collections of algorithms and best-practice protocols offered within the Mass Spectrometry for Proteomics, Gene Expression, and Sequence Analysis Collections.
Biology Collections: Perform advanced analyses on your ‘omics data using the robust collections of algorithms and best-practice protocols offered within the Mass Spectrometry for Proteomics, Gene Expression, Sequence Analysis, and Next Generation Sequencing Component Collections.
Imaging Collection: Manage, process and analyze image data alongside your other data with the Imaging Component Collection.
Analysis and Statistics Collections: Conduct powerful statistical analyses with the implementation of R Statistical Analysis Tools. Perform clustering, Bayesian learning, RP tree learning, similarity searching, and Pareto Optimization with the Modeling and Advanced Data Modeling Component Collections.
Text Analytics Collection: Mine PubMed, US patents, NIH grants and personal documents with the Text Analytics Component Collection.
Symyx notebook by accelrys for biology Streamline the capture of biological information and processes, and improve collaboration with colleagues and contract research organizations, with a flexible, enterprise Electronic Laboratory Notebook (ELN).
- Resources
Learn more about our offerings for Biomarker Research with these resources.
- Multi-Analyte Profiling of Marathon Runners Physiological Genomics Publication: Leading biomarker testing laboratory Rules-Based Medicine used Pipeline Pilot to perform multi-analyte profiling on serum samples taken from marathon runners both before and after running.
- Third-Party PK/PD Application Integration Discussion: Read how Pipeline Pilot can integrate with tools such as NONMEM to help researchers undertake the daunting task of integrating, analyzing and reporting pharmacokinetic and pharmacodynamic data.
- Using Pipeline Pilot to Analyze Biological Threats Poster: Accelrys researchers used Pipeline Pilot in their search for a biomarker of acute lung injury.
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