Translational research has shattered the traditional drug development paradigm. The once-serialized processes of target identification, target validation, and lead optimization are now conducted in parallel and in conjunction with a deep understanding of the patient disease state and/or response to therapy. Additionally, technological developments in deep sequencing, gene expression and proteomics now make it possible to characterize large numbers of client samples.
While this fundamental shift in the drug development paradigm brings hope of shortening development life cycles and improving clinical success rates, it also creates new pain points for researchers who need to work across traditional department barriers in order to access, integrate, and analyze experimental data alongside data from clinical trials.
Accelrys’ award-winning scientific informatics platform, Pipeline Pilot, helps organizations overcome these challenges. Pipeline Pilot unites advanced data mining and analysis tools on a platform that facilitates:
Business-rule creation
Third-party algorithm and application integration
Drag-and-drop workflow building and sharing
Interactive reporting
Accessing and integrating clinical and molecular data is simplified with seamless integration to the BioFortis™ LabMatrix system, an HL7-compliant framework that helps users quickly navigate clinical and molecular data. With Pipeline Pilot, researchers across an organization can successfully conduct and share their translational research.
Additionally, we offer an electronic laboratory notebook, Accelrys Electronic Lab Notebook for Biology, which helps improve operational efficiencies and lower costs by enabling you to plan, execute, and record in vivo and in vitro experiments using a single notebook enterprise-wide.
Products
Pipeline Pilot Graphically combine components for data retrieval, filtering, analysis, and reporting to create and automate translational research workflows.
Pipeline Pilot Component Collections:
NGS Collection: Providing unmatched power and flexibility, the NGS Collection lets you perform genome assembly, mapping, variant detection, RNA-Seq, and ChIP-Seq experiments on data from all major NGS instrumentation platforms.
Imaging Collection: Manage, process and analyze image data alongside your other data with the Imaging Component Collection.
Analysis and Statistics Collections: Conduct powerful statistical analyses with the implementation of R Statistical Analysis Tools. Perform clustering, Bayesian learning, RP tree learning, similarity searching, and Pareto Optimization with the Modeling and Advanced Data Modeling Component Collections.
Accelrys Electronic Lab Notebook for biology Streamline the capture of biological information and processes, and improve collaboration with colleagues and contract research organizations, with a flexible, enterprise Electronic Laboratory Notebook (ELN).
Resources
Learn more about our offerings for Translational Research with these resources:
Third-Party PK/PD Application Integration Discussion: Read how Pipeline Pilot can integrate with tools such as NONMEM to help researchers undertake the daunting task of integrating, analyzing and reporting pharmacokinetic and pharmacodynamic data.