Cheminformatics systems are critical to R&D organizations to capture, manage, analyze, and mine information for chemical samples and to protect IP around those entities. Accelrys supports today's large data volumes and user transactions through a modern, 3-tier, SOA-based, scalable architecture. A powerful underlying chemistry engine empowers a breadth of solutions used to register, query, browse, and report chemical structures, reactions, and biological sequences. The Accelrys chemistry engine has been proven using product databases containing over 30 million molecules and over 17 million reactions.